Table 2

Association analysis of 6 high-LD-group tagging SNPs with five hematological traits by linear regression analysis, controlling for area, age, and sex as covariates
WBC RBC Plat MCV MCHC
CHR SNP BP A1 BETA ± SE P BETA ± SE P BETA ± SE P BETA ± SE P BETA ± SE P
9 rs2073823 135122337 A 0.056 ± 0.039 0.15 0.036 ± 0.008 2.13 × 10-6† −1.213 ± 1.253 0.33 −0.480 ± 0.118 5.06 × 10-5† 0.075 ± 0.029 9.55 × 10-3
9 rs8176720 135122694 C 0.043 ± 0.032 0.19 0.018 ± 0.006 5.58 × 10-3 −0.232 ± 1.033 0.82 −0.071 ± 0.098 0.47 0.025 ± 0.024 0.30
9 rs8176717 135122855 T 0.001 ± 0.039 0.97 −0.012 ± 0.008 0.13 0.885 ± 1.253 0.48 0.356 ± 0.118 2.62 × 10-3† −0.035 ± 0.029 0.22
9 rs687289 135126927 A 0.001 ± 0.032 0.97 0.001 ± 0.006 0.89 1.017 ± 1.025 0.32 −0.274 ± 0.097 4.59 × 10-3 0.020 ± 0.024 0.40
9 rs8176681 135129575 C 0.016 ± 0.035 0.64 0.009 ± 0.007 0.19 −1.488 ± 1.109 0.18 0.063 ± 0.105 0.55 0.003 ± 0.026 0.92
9 rs495828 135144688 T −0.050 ± 0.037 0.18 −0.030 ± 0.007 2.69 × 10-5† 2.217 ± 1.180 0.06 0.061 ± 0.112 0.58 −0.042 ± 0.027 0.12

Note. Chr: chromosome, BP: base pair, A1: minor allele, WBC: white blood cell count, RBC: red blood cell count, Platelet, MCV: mean corpuscular volume, MCHC: mean corpuscular hemoglobin concentration.

Underlined p-values were passed the multiple correction criteria of Bonferroni correction (p<0.008).

Significant result after adjusted by rs2073823.

Hong et al.

Hong et al. BMC Genetics 2012 13:78   doi:10.1186/1471-2156-13-78

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