Table 1

Patient and quality control characteristics by sample type
N All Buccal Blood
850 708 (83%) 142 (17%)
Patient
Age (years ± SD) 66.7 ± 14.8 67.2 ± 14.8 64.6 ± 14.9
Sex (% male) 417 (49.1%) 348 (49.2%) 69 (48.6%)
Stroke status (% cases) 433 (50.9%) 353 (49.9%) 80 (56.3%)
Cigarette smoker (% current) 163 (19.2%) 136 (19.2%) 27 (19.0%)
Pre-genotyping QC
QC Failure (%)a 90 (10.6%) 80 (11.3%) 10 (7.0%)
cQC <0.4 75 (8.8%) 69 (9.7%) 6 (4.2%)
 DM call rate <83% 65 (7.6%) 60 (8.5%) 5 (3.5%)
 Gender mismatch 24 (2.8%) 19 (2.7%) 5 (3.5%)
 cQC rate 2.08 ± 0.94 2.00 ± 0.94 2.53 ± 0.82***
 Among passed samples 2.33 ± 0.65 2.24 ± 0.65 2.69 ± 0.55***
 Among failed samples 0.05 ± 0.43 0.01 ± 0.37 0.36 ± 0.71
DM call rate 93.1 ± 7.8% 92.7 ± 8.3% 95.1 ± 4.0% ***
 Among passed samples 95.3 ± 2.8% 95.1 ± 2.9% 96.0 ± 1.9% ***
 Among failed samples 74.7 ± 11.7% 73.5 ± 11.7% 83.9 ± 6.9% **

N (%) or mean ± SD presented.

a Failure subsets do not add to total failed samples, as samples frequently fail for more than one reason.

** p < 0.01 blood vs. buccal samples; ***p < 0.0001 blood vs. buccal samples.

Woo et al.

Woo et al. BMC Genetics 2012 13:75   doi:10.1186/1471-2156-13-75

Open Data