Open Access Research article

Pseudogenization of the MCP-2/CCL8 chemokine gene in European rabbit (genus Oryctolagus), but not in species of Cottontail rabbit (Sylvilagus) and Hare (Lepus)

Wessel van der Loo12*, Sandra Afonso13, Ana Lemos de Matos123, Joana Abrantes124 and Pedro J Esteves15

Author Affiliations

1 CIBIO-UP, Centro de Investigação em Biodiversidade e Recursos Genéticos, Campus Agrário de Vairão, Universidade do Porto, Vairão, 4485-661, Portugal

2 Departamento de Zoologia e Antropologia, Faculdade de Ciências, Universidade do Porto, Porto, 4169-007, Portugal

3 Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, 60153, USA

4 INSERM U892 - Institut de Biologie Equipe 5, Nantes, Cedex 01, 44007, France

5 Centro de Investigação em Tecnologias da Saúde, IPSN, CESPU, Gandra, 4585-116, Portugal

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BMC Genetics 2012, 13:72  doi:10.1186/1471-2156-13-72

Published: 15 August 2012

Additional files

Additional file 1:

GenBank Features file for RabbitNC_013687REGION: 23720000.23798000.

Format: DOC Size: 34KB Download file

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Open Data

Additional file 2:

Alignment of Oryctolagus cuniculus and Homo sapiens WGS sequences: identifying rabbit ortholog of human CCL7.

Format: DOC Size: 46KB Download file

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Additional file 3:

Alignment of Oryctolagus cuniculus and Homo sapiens WGS sequences: identifying the rabbit ortholog of human CCL8.

Format: DOC Size: 51KB Download file

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Additional file 4:

Alignment of Oryctolagus cuniculus and Homo sapiens WGS sequences: identifying rabbit ortholog of human CCL13.

Format: DOC Size: 46KB Download file

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Additional file 5:

Alignment of MCP encoding regions of rabbit and human in Fasta format.

Format: DOC Size: 315KB Download file

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Additional file 6:

Rabbit CCL13 ortholog named ‘ CCL8’ or ‘ CCL7’.

Format: DOC Size: 60KB Download file

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Additional file 7:

Nucleotide variation at CCL8 genes within and among leporid species.

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Additional file 8:

Detailed PCR procedures.

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Additional file 9:

Genbank Accessions and Links of MCP-Eotaxin mRNA sequences of Placental Mammals used or consulted.

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