Open Access Highly Accessed Research article

Runs of homozygosity and population history in cattle

Deirdre C Purfield12, Donagh P Berry2, Sinead McParland2 and Daniel G Bradley1*

Author Affiliations

1 Smurfit Institute of Genetics, University of Dublin, Trinity College, Dublin 2, Ireland

2 Animal & Grassland Research and Innovation Center, Teagasc, Moorepark, Fermoy, Co, Cork, Ireland

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BMC Genetics 2012, 13:70  doi:10.1186/1471-2156-13-70

Published: 14 August 2012

Additional files

Additional file 1:

Details of animals genotyped with the Bovine SNP50 density panel.

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Additional file 2:

The number of runs of homozygosity (ROH), in the HD panel population, per chromosome (bars) and the mean per animal percentage coverage of the chromosome covered by ROH graph.

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Additional file 3:

The maximum amount of overlapping runs of homozygosity (ROH) per chromosome and the percentage of overlapping ROHs that are a >95% allelic match graph.

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Additional file 4:

Proportion of appearances of each SNP on chromosome 14 in a ROH across dairy, beef and British animals graph.

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Additional file 5:

Linkage disequilibrium plot using Haploview of the consensus overlap segment located on chromosome in 86% of the ROH.

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Additional file 6:

Linkage disequilibrium plot using Haploview of SNPs on chromosome 12 that did not appear in a ROH.

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Additional file 7:

Average total sum of Runs of Homozygosity (ROH) per animal within breed vs the number of validated polymorphic loci in the Bovine SNP50 genotyping beadchip graph.

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