Accuracy of SupportMix. Accuracy of SupportMix ancestry assignments for in silico generated admixed populations. (A) Accuracy of ancestry assignment for two-way admixture between all HGDP populations (with more than 10 sampled individuals) using SupportMix (blue dots) and for a subset of 7 populations listed in legend using LAMP (red dots with the corresponding SupportMix results circled in red). Each in silico admixed population is plotted on the x-axis by the level of populations structure between the two ancestral populations as measured by fixation index, Fst. (B) The effects of time since admixture, measured in generations, on SupportMix accuracy for 7 populations. (C) Effect on accuracy of uncertainty in generations since admixture, where g′ = 5 was the number of generations used to simulate the populations and g was the parameter used in SupportMix, which varied between .25 and 100 generations. (D) Effect of window size used on SupportMix accuracy of ancestry assignments.
Omberg et al. BMC Genetics 2012 13:49 doi:10.1186/1471-2156-13-49