Analytical Strategy for 'Parallel Analysis' of Chromosome 5q31 Region. This figure details the study design, cardiovascular cohorts and analytic techniques used, and the number of unique genes containing SNPs with significant associations (indicated underneath the method used). The union of quantitative results (α) indicates the subset of genes shared by the two methods. The qualitative trait (CVD) was analyzed in GENECARD, CATHGEN, and aortas and the total number of unique genes containing a significant SNP in any of those analyses is indicated. The commonality of the genes between the quantitative and qualitative analyses (N = 9, PRELID2, SPOCK1, EBF1, PPP2R2B, DMXL1, DTWD2, GABRG2, GLRA1, and RP11-166A12.1) is indicated by ω.
Nolan et al. BMC Genetics 2012 13:12 doi:10.1186/1471-2156-13-12