Open Access Research article

Genetic effects and correlations between production and fertility traits and their dependency on the lactation-stage in Holstein Friesians

Eva M Strucken1, Ralf H Bortfeldt1, Jens Tetens2, Georg Thaller2 and Gudrun A Brockmann1*

Author Affiliations

1 Breeding Biology and Molecular Genetics, Humboldt-Universität zu Berlin, Invalidenstraße 42, Berlin, 10115, Germany

2 Animal Breeding and Husbandry, Christian-Albrechts Universität zu Kiel, Olshausenstr. 40, Kiel, 24098, Germany

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BMC Genetics 2012, 13:108  doi:10.1186/1471-2156-13-108

Published: 17 December 2012

Additional files

Additional file 1 Table S1:

Complete list of significant markers over the first 60 lactation days separated after 10-day intervals. DIM: days in milk; MY: milk yield; FY: fat yield; PY: protein yield; FC: fat content; PC: protein conten.

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Additional file 2 Table S2:

Complete list of markers significant for the 305-day records. MY: milk yield; FY: fat yield; PY: protein yield; FC: fat content; PC: protein content.

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Additional file 3 Table S3:

Additional markers detected when accounting for the DGAT1 locus. DIM: days in milk; MY: milk yield; FY: fat yield; PY: protein yield; FC: fat content; PC: protein content. Effects, SD and P-values are given as the results from the analysis without DGAT1 in the model and in brackets with DGAT1 in the model.

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Additional file 4 Table S4:

Significant markers and allele effects for fertility traits. RZR: fertility index, summarizing all fertility traits, NRh: non-return rate for heifers.

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Additional file 5 Table S5:

LSM-differences between the first 60 lactation days separated after effect groups. P-values *** < 0.0001 ** < 0.001 * < 0.01 † < 0.05. LSM: least square means; DIM: days in milk; MY: milk yield; FY: fat yield; FC: fat content; PC: protein content.

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Additional file 6 Table S6:

LSM- differences between the 10-day intervals over the first 60 lactation days and 305-day records after effect groups. P-values *** < 0.0001 ** < 0.001 * < 0.01 † < 0.05. LSM: least square means; DIM: days in milk; FC: fat content; PC: protein content.

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Additional file 7 Table S7:

Haplotype blocks, marker and candidate gene information over all approaches. HTB: haplotype block; DIM: days in milk; MAF: minor allele frequency; MY: milk yield; FY: fat yield; PY: protein yield; FC: fat content; PC: protein content; RZR: fertility index, summarizing all fertility traits; NRh: non-return rate for heifers; ns: non-significant. * only significant when DGAT1 region was deducted; allele effects are given as original results due to the bias when a major locus is deducted.

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Additional file 8 Table S8:

EBVs for 305-day production traits. EBV: estimated breeding value; MY: milk yield; FY: fat yield; PY: protein yield; FC: fat content; PC: protein content.

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Additional file 9 Figure S1:

Average EBVs over first 60 lactation days. EBV: estimated breeding value; filled triangle milk yield; filled circle fat yield; filled square protein yield; empty circle fat content; empty square protein content (axis for milk yield is on the right hand side).

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Additional file 10 Table S9:

EBVs for fertility traits. EBV: estimated breeding value; RZR: fertility index, summarizing all following traits, FLc and FLh: 1st to successful insemination separated after cows and heifers, NRc and NRh: non-return rate for cows and heifers, CON: conception (summarizing FLc and FLh, NRc and NRh), CFc: calving to first insemination; DO: and days open.

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