BMC Genetics

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The impact of modern migrations on present-day multi-ethnic Argentina as recorded on the mitochondrial DNA genome

María L Catelli1, Vanesa Álvarez-Iglesias2, Alberto Gómez-Carballa2, Ana Mosquera-Miguel2, Carola Romanini1, Alicia Borosky3, Jorge Amigo2, Ángel Carracedo2, Carlos Vullo1,3 and Antonio Salas2*

Author Affiliations

1 Equipo Argentino de Antropología Forense, Independencia 644 - 5C, Edif. EME1, Córdoba, Argentina

2 Unidade de Xenética, Instituto de Medicina Legal and Departamento de Anatomía Patolóxica e Ciencias Forenses, Calle San Francisco sn, Facultade de Medicina, Universidade de Santiago de Compostela, CIBERER, Santiago de Compostela, 15782, Galicia, Spain

3 Laboratorio de Inmunogenética y Diagnóstico Molecular, Independencia 644 - 4, Edif EME1, Córdoba, Argentina

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BMC Genetics 2011, 12:77 doi:10.1186/1471-2156-12-77

Published: 30 August 2011

Additional files

Additional file 1:

Table S1. List of samples analyzed in the present study and collected from the literature (American neighboring countries and European ones) used for admixture analysis.

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Additional file 2:

Table S2. Haplotype and mtSNP profiles of the Argentinean samples analyzed in the present study.

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Additional file 3:

Figure S1. Simulation aimed to demonstrate that Italy and Spain are sufficiently different in terms of haplotype sharing, therefore, supporting the results of admixture analysis. First, two databases were considered jointly, the Spanish (n = 1467) and the Italian database (n = 1667) (see Additional file 1: Table S1, and text for more information on the databases). From this global database (n = 3134), two samples of sizes 1467 and 1667 each were taken at random without replacement 10,000 times. The distribution represents the number of identical shared haplotypes (horizontal axis) and their counts (vertical axis) between the 10,000 pairs of random samples. The red line indicates the observed number of haplotypes shared between the Italian and the Spanish database (n = 134; see also Figure 2).

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Additional file 4:

Figure S2. Patterns of haplotype frequencies in Argentinean population samples. Only those samples of sizes > 20 individuals were considered.

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Additional file 5:

Figure S3. Pairwise FST values (A), and average number of pairwise differences within and between populations and Nei's distances (B).

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