Table 2

Technical evaluation of the "610k", "Omni1", and "Axiom" studies.

"610k"

"Omni1"

"Axiom"


Subjects

1808 (100)

1283 (100)

1550 (100)

Positive amplification

1799 (99.5)

1283 (100)

1550 (100)

Successful genotyping

1778 (98.8)

1278 (99.6)

1530 (98.7)

Requeue

60 (3.34)

18 (1.40)

Successfully requeued

39 (65.0)

13 (72.2)

Methodological replicates

6 (99.999)

32 (99.994)

Technical replicates

11 (99.950)

16 (99.998)


Number and percentage (%) of included subjects. Subjects: number of subjects initially included. Positive amplification: number of subjects with a successful WGA reaction (conc. > 30 ng/ul). Requeue: gDNA samples failing to reach initial successful genotyping criteria that were whole-genome amplified and genotyped a second time. Successfully requeued: The number of requeued samples successfully genotyped. Methodological replicates: the same gDNA sample amplified twice and genotyped separately. Technical replicates: the same wgaDNA sample run twice on separate chips.

Hollegaard et al. BMC Genetics 2011 12:58   doi:10.1186/1471-2156-12-58

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