Table 2

Allelic Effect on Trait Distribution in the Two Ancestry Groups.

PUFA

Group

p-value

allelic effect β (95% CI)


DGLA

African American

2.23 × 10-04

0.225 (0.105,0.344)

European American

9.53 × 10-05

0.162 (0.081,0.244)


AA

African American

3.72 × 10-05

-1.133 (-1.671,-0.594)

European American

9.28 × 10-23

-1.461 (-1.754,-1.170)


AA/DGLA

African American

6.07 × 10-15

-1.483 (-1.855,-1.110)

European American

6.34 × 10-19

-1.172 (-1.431,-0.914)


Allelic effect on trait distributions of age- and gender-adjusted ω6 PUFAs (AA and DGLA) and FADS1 enzymatic efficiency (AA/DGLA) was examined in the African Americans and European Americans from the GeneSTAR Study at marker rs174537.

Mathias et al. BMC Genetics 2011 12:50   doi:10.1186/1471-2156-12-50

Open Data