Table 2

Summary of the LCA-SEM partition using systolic and diastolic blood pressure as indicators

Entropyb

Model

Number of subpopulations

Co-variates in decreasing order of significansa

With covariates

Change

% Normalizedd

Correlation of indicatorse

Excluding CRP and BNP


Average 24 hours

14

CRP HomaRes Compliance Supar VLDL Aasi WH BNP ApoE

0.789

-2.3%

66.9%

81.8%

71.4%

Average daytime

12

CRP HomaRes Compliance Supar VLDL WH BNP ApoE Aasi ApoA1

0.788

+5.3%

61.1%

75.0%

83.3%

Average night

13

CRP HomaRes Compliance Supar VLDL BNP ApoE

0.747

-9.3%

64.1%

79.5%

84.6%

Sitting (office BP)

11

CRP Compliance VLDL Homares Age BNP BMI ApoA1

0.724

-1.0%

50.0%

69.1%

81.8%

Supine

14

HomaRes BNP Compliance Supar VLDL CRP Age BMI ApoA1

0.792

+2.5%

68.8%

80.5%

100.0%

UL4c

12

HomaRes CRP Supar BNP VLDL ApoA1 ApoE

0.759

-5.8%

47.0%

65.2%

80.6%

UL2c

14

HomaRes BNP Compliance Supar VLDL CRP ApoA1 Age BMI

0.801

+5.8%

68.7%

80.8%

28.6%


a CRP, C-reactive protein; HomaRes, insulin resistance;VLDL, very low densitity lipoprotein; Aasi, vessel stifness; WH, waist-hip ratio; BNP, B-type or brain natriuretic peptide; BMI, body mass index; Apo, apolipoprotein; Supar, soluble urokinase activator receptor.

b Entropy for the full model as defined in the MPlus programme (1 - standard entropy) for the error structure. Changes signifies deviation from the model without covariates.

c Ultrasound recording of systolic and diatolic blood pressure: UL4, left and rigth measurements are seperate indicators;

UL2, average of left and right systelic and diastolic blood pressure, respectively, are used as indicators

d Fraction of traits in all classes normalized by the LCA-SEM partition. Only the traits listed and the mode of blood pressure measurements are included in the calculation

e Fraction of indicators not correalted after LCA-SEM partition

Fenger et al. BMC Genetics 2011 12:44   doi:10.1186/1471-2156-12-44

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