Table 3

Regions significantly (-log10(P-value ≥ 3)) associated with fatty acids and the percentage of the total additive genetic variance explained

Region

Start

(Mbp)

End

(Mbp)

# SNP in region

Trait

#Traits/region


C4:0

C6:0

C8:0

C10:0

C12:0

C14:0

C16:0

C18:0

C10:1

C12:1

C14:1

C16:1

C18:1

CLA


1a

24.8

24.8

2

3.3

1

1b

54.1

62.8

148

0.9

2.0

2

1c

121.5

129.9

120

3.0

1

1d

146.4

161.0

304

2.1

1

2a

27.6

27.7

3

1.8

1

2b

44.3

69.5

351

2.7

1

2c

126.1

139.5

257

4.0

3.3

2

3a

22.2

25.1

55

4.1

1

3b

125.2

126.9

39

2.9

5.3

2

4

121.8

123.7

30

2.2

1

5a

65.9

65.9

3

1.5

1

5b

81.9

99.9

275

2.7

4.8

2

5c

107.5

113.6

104

1.8

2.7

2

6a

31.4

45.2

630

4.3

1.3

3.1

3

6b

111.2

115.6

81

4.2

1

7a

10.7

23.8

206

4.1

3.9

3.3

4.3

4

7b

62.4

64.2

46

2.0

7.4

3.4

3.0

4

7c

100.3

110.7

166

3.1

1

8a

20.5

21.9

28

2.7

1

8b

52.7

58.4

104

4.5

4.2

2

8c

76.9

101.5

406

1.3

2.4

2

9a

21.4

21.6

2

1.1

1

9b

36.7

36.7

3

3.9

1

9c

48.8

50.4

25

3.9

1

9d

66.6

67.0

4

4.8

1

10a

8.3

8.3

3

1.2

1

10b

98.8

100.2

34

2.8

1

11

35.2

48.0

218

2.3

1

12

52.4

60.1

116

2.2

2.8

2

13

49.5

71.5

377

3.0

2.2

1.9

4.4

3.3

5

14a

0.0

26.3

1121

4.9

2.2

17.7

39.6

6.2

4.8

4.5

34.8

61.9

12.2

10

14b

40.0

40.8

7

3.7

1

15a

20.5

27.0

121

1.2

1.8

2

15b

60.7

65.1

63

3.4

1

15c

72.3

77.7

103

3.8

1

16

53.2

53.5

9

2.3

1

17a

31.4

34.3

43

2.9

1.9

2

17b

68.7

68.7

3

3.5

3.0

2

18a

14.1

29.5

305

1.8

3.1

3.5

3

18b

53.6

54.9

15

1.9

1

19a

6.1

6.1

3

2.3

1

19b

32.7

61.8

529

6.5

3.0

4.4

5.3

13.8

3.0

7.1

3.9

8

20

72.9

73.6

18

1.6

1

21

5.8

5.8

4

3.0

1

22

8.9

42.4

593

3.9

3.5

2

23

26.3

31.7

141

2.9

1

24a

40.4

49.1

142

1.3

1

24b

56.4

58.6

27

2.2

1

25

42.9

42.9

2

1.5

1

26

2.5

41.2

724

3.3

4.5

4.8

35.4

20.5

67.8

23.2

7

27

28.7

48.3

358

2.7

3.7

7.6

4.1

4.4

3.2

6

28a

6.8

13.2

116

2.8

1

28b

19.7

19.7

2

2.9

1

X

85.2

86.4

16

2.0

1


Sum

8,605

14.9

11.2

10.3

18.9

5.3

68.7

54.7

7.4

77.1

48.7

114.0

102.3

82.6

26.5

All SNPs simultaneous in model2

14.9

10.2

10.9

16.3

5.3

41.8

53.9

7.4

62.0

45.2

97.4

79.2

78.6

24.1

# Regions/trait

3

3

4

10

1

19

5

1

11

8

14

18

5

5

107


1 A region starts at the first significant SNP and proceeds if the next significant SNP is positioned within the next 10 Mbp on the same chromosome, ending at the position of the last significant SNP matching this requirement, with a minimum of 2 significant SNP per trait in a region. The number of the region stands for the BTA number plus an a, b, c or d indicating different regions within a BTA.

2 Percentage of the total additive genetic variance explained by all the most significant SNPs per region together. This was analyzed with the animal model and all the most significant SNPs per region simultaneous in the model.

Percentage of total additive genetic variance explained by the most significant SNP associated with the trait per region, analyzed with an animal model.

Bouwman et al. BMC Genetics 2011 12:43   doi:10.1186/1471-2156-12-43

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