Table 4

Median Odds Ratios and Powers in Joint Analysis (Stage One and Stage Two Combined)

Number of Selections

Joint Analysis

p-Value-Based Ranking Approach

Hybrid Ranking Approach

M₁

M₂

M₁

M₂

10

OR

1.7387

1.4467

1.6866

1.4447

Power at 1.7 × 10^-7

51.2%

87.0%

79.4%

84.2%

20

OR

1.7342

1.4418

1.6787

1.4467

Power at 1.7 × 10^-7

56.3%

90.9%

80.0%

87.0%

30

OR

1.7343

1.4363

1.6801

1.4398

Power at 1.7 × 10^-7

58.9%

92.3%

79.7%

90.4%

40

OR

1.7224

1.4379

1.6761

1.4418

Power at 1.7 × 10^-7

60.6%

93.0%

81.2%

90.9%

OR = odds ratio.

Wang and Shete BMC Genetics 2011 12:3   doi:10.1186/1471-2156-12-3