Table 3

Power to Select Top Single-Nucleotide Polymorphisms in Stage One for Replication Based on 1,000 Replicates

Number of Selections

p-Value-Based Ranking Approach

Hybrid Ranking Approach


M1

M2

M1

M2


10

52.2%

87.0%

88.9%

84.2%

20

57.9%

90.9%

89.9%

87.0%

30

61.1%

92.4%

90.4%

90.4%

40

62.6%

93.0%

91.2%

90.9%


OR = odds ratio.

MAF was set at 10% for M1 and 40% for M2.

Wang and Shete BMC Genetics 2011 12:3   doi:10.1186/1471-2156-12-3

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