Table 1 |
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|
Parameters for Simulation under Alternative Hypothesis |
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|
Disease Locus 1 |
Marker 1 |
Disease Locus 2 |
Marker 2 |
|
|
(D1) |
(M1) |
(D2) |
(M2) |
|
|
|
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|
OR |
1.8 |
1.5 |
||
|
MAF |
10% |
10% |
40% |
40% |
|
|
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|
OR = odds ratio, MAF = minor allele frequency, LD = linkage disequilibrium. The LD between the disease loci and the corresponding marker loci is 0.8, and the two disease loci are in linkage equilibrium. |
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|
Wang and Shete BMC Genetics 2011 12:3 doi:10.1186/1471-2156-12-3 |
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