Table 2

Association between a range of milk production variables in cows and (i) replacing a T allele with a C allele in the TLR4-2021 SNP (standard error in parenthesis), and (ii) TLR4-2021 genotypes

Genotype1


Trait

Mean Trait Value2

Allele Substitution

(T→C)

P-value

TT

TC

CC

P-value


Milk Yield (kg)

4455 (1200)

-65.7 (137.9)

NS

0

-22.81 (226.7)

-96.04 (282.8)

NS

Protein Yield (kg)

164 (40)

-3.86 (4.56)

NS

0

-1.64 (7.48)

-6.24 (9.34)

NS

Fat Yield (kg)

197 (51)

-4.88 (5.25)

NS

0

1.24 (8.63)

-7.01 (10.77)

NS

Lactose Yield (kg)

206 (52)

-1.29 (5.83)

NS

0

-1.68 (9.55)

-1.63 (11.93)

NS

Protein Percentage3 (*1000)

36 (3)

-0.39 (0.19)

< 0.05

0

0.03 (0.32)

-0.63 (0.39)

< 0.05

Fat Percentage3 (*1000)

44 (8)

-0.69 (0.44)

NS

0

0.77 (0.72)

- 0.97 (0.9)

< 0.01

SCS (loge SCC)

1.67 (0.46)

-0.05 (0.05)

NS

0

-0.08 (0.07)

-0.11 (0.09)

NS


1 Referent class is the TT genotype and is compared with the CT and CC genotype

2 Mean values observed for each phenotype investigated (standard deviation in parenthesis)

3 A value of 1, before multiplication, equates to 1 percentage unit

NS = Not significant

Beecher et al. BMC Genetics 2010 11:99   doi:10.1186/1471-2156-11-99

Open Data