Table 3

Genotype distributions, odds ratios (OR), and their 95% confidence intervals (CI) and p-values for the genetic models

p-value


Gene

SNPs ID

Genotype

Counts

(Controls/Cases)

OR

95% CI

General association

Dominant

Additive

Recessive


VDR

rs10735810

C/C

41/29

1

0.24

0.57

0.80

0.18

T/C

58/30

0.71

0.38-1.35

T/T

11/10

1.50

0.60-3.78

rs1544410

G/G

46/17

1

0.15

0.08

0.22

0.91

G/A

58/25

0.54

0.28-1.01

A/A

16/10

0.78

0.32-1.91

rs731236

T/T

49/37

1

0.32

0.15

0.30

0.96

T/C

54/25

0.61

0.32-1.16

C/C

17/10

0.78

0.32-1.90

IL6

rs1800795

G/G

35/15

1

0.27

0.20

0.63

0.59

G/C

56/42

1.75

0.85-3.61

C/C

29/15

1.21

0.51-2.88

CTR

rs1922295

T/T

59/45

1

0.12

0.07

0.22

0.81

T/C

49/19

0.51

0.25-0.98

C/C

12/8

0.87

0.33-2.32

COL1A1

rs1800012

G/G

85/53

1

0.48

0.68

0.91

0.30

G/T

34/17

0.80

0.41-1.58

T/T

1/2

3.21

0.28-36.25

rs2696247

T/T

189/100

1

0.45

-

-

-

T/C

123/88

1.27

0.68-2.35

rs2586488

C/C

50/30

1

0.09

1.0

0.30

0.041

C/T

58/27

0.78

0.41-1.48

T/T

12/15

2.08

0.86-5.04

COL1A2

rs406226

A/A

86/50

1

0.14

0.74

0.49

-

A/G

34/20

1.01

0.53-1.94

G/G

0/2

-

-

rs2301643

G/G

88/50

1

0.13

0.56

0.35

-

G/A

32/20

1.10

0.57-2.12

A/A

0/2

-

-

rs3216902

Ins/Ins

52/29

1

0.05

0.68

0.46

0.032

Ins/NoI

47/38

1.45

0.78-2.71

NoI/NoI

21/5

0.43

0.15-1.25

LRP5

rs2277268

G/G

111/59

1

0.03

-

-

-

G/A

9/13

2.72

1.10-6.73

rs4988321

G/G

115/65

1

0.13

-

-

-

G/A

5/7

2.48

0.76-8.12

rs556442

A/A

82/43

1

0.36

0.23

0.17

0.30

A/G

36/26

1.38

0.74-2.57

G/G

2/3

2.86

0.46-17.78

rs3736228

C/C

107/62

1

0.53

-

-

-

C/T

13/100

1.33

0.55-3.21


1OR = 2.37, 95% CI 1.04-5.40. 2OR = 0.35, 95% CI 0.13-0.98. Body mass index (BMI) was used as a covariate in the analyses.

Korvala et al. BMC Genetics 2010 11:95   doi:10.1186/1471-2156-11-95

Open Data