Effect of age group on PROP sensitivity by common diplotypes. The cumulative percentage of subjects with the following diplotypes (A) taster PAV/PAV, (B) heterozygous AVI/PAV, and (C) nontaster AVI/AVI who first reported a bitter taste when sampling 56 (black bars), 180 (grey bars), and 560 μM PROP (hatched bars) or who never reported a bitter taste when sampling each of these PROP solutions (white bars). In panel (B) there is an increase in the proportion of children who report a bitter taste for the 56 μmol/liter solution relative to adults. *denotes a significant difference by χ2 partition.
Mennella et al. BMC Genetics 2010 11:60 doi:10.1186/1471-2156-11-60