Additional file 2.

Plot of chr1SNP fluorescence data with conventional Cartesian thresholds and thresholds generated by the polar coordinate histogram method. Samples (n = 357) were genotyped at Chr1SNP using the LDR-FMA method. Allele calls were then made using both the conventional methods (3× standard deviations above the mean of known negative samples) and by the polar coordinate histogram method. Conventional thresholds are indicated by the red dotted line, and the polar thresholds are indicated by the black solid line with the black dotted line showing the 95% confidence intervals.

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DaRe et al. BMC Genetics 2010 11:57   doi:10.1186/1471-2156-11-57