Table 1

Association of microsatellite markers with epilepsy in Belgian Tervuren dogs on chromosomal regions exhibiting suggestive linkage

CFA Position Mb

Marker

PIC

Two-Point Epilepsya

Two-Point Age at Onsetb

Multi-point LODc

Fisher Exact*

Cri-Map LOD

TDT*

Sib-Pair*

Hap block*


CFA02

7.16

FH2274

0.41

0.615

0.715

0.63

0.0018

0.02

0.002

0.175

10.35

v170

0.57

0.396

0.781

0.785

0.0001

0

0.000

0.333

0.04

15.5

v163

0.55

1.095

1.616

0.802

0.0005

0

0.000

0.413

43.23

v200

0.65

0.037

0.129

0.074

0.0067

0

0.388

0.142

46.62

v205

0.56

1.063

1.447

0.08

0.3283

0.24

0.005

0.144

69.34

v235

0.63

0.252

0.133

0.864

0.0104

0.24

0.002

0.56

73.02

v240

0.69

1.001

1.415

0.834

0.0076

0.84

0.001

0.097

0.05

78.35

AHT111

0.59

0.01

0.068

0.733

0.0003

0.38

0.009

0.542

81.01

FH3965

0.78

0.15

0.031

0.735

0.7088

1.13

0.363

0.102

CFA06

15.58

v620

0.41

1.057

1.024

0.236

0.6055

0.15

0.786

0.12

0.008

26.16

v633

0.34

0.251

0.362

0.015

0.6572

0

0.876

0.447

30.97

v639

0.70

0.073

0.161

0.004

0.0283

0.02

0.000

0.454

CFA12

24.28

1-21-3

0.68

0.719

0.79

0.625

0.114

0.31

0.000

0.999

24.28

FH2054

0.67

1.212

1.26

0.634

0.5973

0.83

0.010

0.464

27.72

FH2401

0.61

0.15

0.448

0.688

0.667

0

0.094

0.844

35.37

v1172

0.39

0

0.077

0.751

0.6036

0

0.010

0.905

44.55

FH3591

0.85

1.221

1.369

0.788

0.3102

0.2

0.002

0.929

0.035

CFA37

18.09

AHT133

0.53

0.048

0.066

0.217

0.0021

0

0.013

0.288

0.003

22.39

Ren67c18

0.59

0.391

0.528

0.960

0.007

0

0.016

0.025


a Two-point LOD scores for the binary trait of epilepsy

b Two-point LOD scores for the continuous trait of age at onset

c Highest multipoint LOD score for the binary trait of epilepsy nearest the associated marker

*P-values

Oberbauer et al. BMC Genetics 2010 11:35   doi:10.1186/1471-2156-11-35

Open Data