Table 6

Associations between SNP alleles and dark versus light hair colour in 210 Danes.

Gene

Chr.

Positiona

SNP

Min. allele

MAFb

Fisher's Exact

ORd

Hair colour


HPS3

3

Int 5

rs2254913c

A

0.45

1.00


Int 8

rs6785780

T

0.44

0.048

1.6

Light


DTNBP1

6

Exon 10

S191P

rs17470454

A

0.07

0.32


Int 6

rs6909929

A

0.42

0.37


ERCC6

10

3'UTR

rs4253231

C

0.10

0.56


CYP2C8

10

Int 8

rs11572177

G

0.27

0.60


TYR

11

Int 3

rs12421746

T

0.04

0.043

3.1

Light


KITLG

12

Int 1

rs10777129

A

0.07

0.013

3.0

Light

Int 1

rs1492354

A

0.08

0.031

2.5

Light


DCT

13

Int 6

rs9584233

T

0.12

1.00


GNAS

20

Int 1

rs4810147c

A

0.50

0.60


Int 6

rs234630

C

0.23

0.38

Int 6

rs919197

T

0.50

0.86


a: Intron (Int), Exon or Untranslated region (UTR) position in the gene

b: Minor allele frequency (MAF)

c: alleles slightly out of Hardy Weinberg Equilibrium

d: Odds ratios (OR) are only calculated for statistically significant associations

Mengel-From et al. BMC Genetics 2009 10:88   doi:10.1186/1471-2156-10-88

Open Data