Table 5

Associations between SNP alleles and dark versus light hair colour in 378 Danes.

Gene

Chr.

Positiona

SNP

Min.allele

MAFb

p-value

ORe

Hair colour


MATP

5

Exon 5 L374F

rs16891982

C

0.02

0.005

7.0

Dark

Exon 3

K272E

rs26722

A

0.02

0.07

Dark


HERC2

15

Int 12

rs916977c

T

0.07

8.3 × 19-5 d

3.7

Dark

3'UTR

rs1129038c

C

0.11

2.0 × 10-6 d

3.5

Dark

Exon 78

Q3989Q

rs11636232

T

0.46

0.098

Int 44

rs2238289

G

0.07

2.2 × 10-5 d

4.0

Dark

Int 56

rs7170852

A

0.09

1.7 × 10-5 d

3.5

Dark


OCA2

15

Exon 9

W305R

rs1800401

T

0.04

0.75

Exon 13 Q419R

rs1800407

A

0.04

0.31


MC1R

16

5' UTR

rs3212359

A

0.34

0.17

5' UTR

rs3212361

T

0.27

0.055

V60L

rs1805005

A

0.12

0.20

V92M

rs2228479

A

0.07

0.22

R151C

rs1805007

T

0.09

0.70

R160W

rs1805008

T

0.08

0.055

R163Q

rs885479

T

0.04

1.0

T314T

rs2228478c

G

0.09

1.0


a: Intron (Int), Exon or Untranslated region (UTR) position in the gene

b: Minor allele frequency (MAF)

c: alleles slightly out of Hardy Weinberg Equilibrium

d: Significant using Bonferroni correction. Other p-values were corrected by empirical permutation

e: Odds ratios are only shown for statistically significant associations

Mengel-From et al. BMC Genetics 2009 10:88   doi:10.1186/1471-2156-10-88

Open Data