Table 7

Epistatic model - mixed (EPI RD).

Low risk

High risk

r1 = 2; r2 = 4

r1 = 5; r2 = 10


Theoretical penetrance matrix


Neural network

Mean absolute difference E

Sum

0.2239

0.1563


Logistic regression

Mean absolute difference E

Sum

0.5105

0.8658


Logistic regression (design variables)

Mean absolute difference E

Sum

0.2799

0.2329


Mean absolute differences between theoretical and estimated penetrance matrices from 100 replications in the low and high risk scenario.

G√ľnther et al. BMC Genetics 2009 10:87   doi:10.1186/1471-2156-10-87

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