Table 5

Epistatic model - recessive (EPI RR).

Low risk

High risk

r = 5

r = 10


Theoretical penetrance matrix


Neural network

Mean absolute difference E

Sum

0.2071

0.1410


Logistic regression

Mean absolute difference E

Sum

0.4849

0.6150


Logistic regression (design variables)

Mean absolute difference E

Sum

0.3503

0.2755


Mean absolute differences between theoretical and estimated penetrance matrices from 100 replications in the low and high risk scenario.

G√ľnther et al. BMC Genetics 2009 10:87   doi:10.1186/1471-2156-10-87

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