Table 5 

Epistatic model  recessive (EPI RR). 

Low risk 
High risk 

r = 5 
r = 10 



Theoretical penetrance matrix 



Neural network 

Mean absolute difference E 

Sum 
0.2071 
0.1410 


Logistic regression 

Mean absolute difference E 

Sum 
0.4849 
0.6150 


Logistic regression (design variables) 

Mean absolute difference E 

Sum 
0.3503 
0.2755 


Mean absolute differences between theoretical and estimated penetrance matrices from 100 replications in the low and high risk scenario. 

Günther et al. BMC Genetics 2009 10:87 doi:10.1186/147121561087 