Open Access Highly Accessed Research article

Developing a set of ancestry-sensitive DNA markers reflecting continental origins of humans

Paula Kersbergen12, Kate van Duijn3, Ate D Kloosterman1, Johan T den Dunnen2, Manfred Kayser3 and Peter de Knijff2*

Author Affiliations

1 Department of Human Biological Traces (R&D), Netherlands Forensic Institute, PO Box 24044, 2490 AA The Hague, The Netherlands

2 Department of Human and Clinical Genetics, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands

3 Department of Forensic Molecular Biology, Erasmus University Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands

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BMC Genetics 2009, 10:69  doi:10.1186/1471-2156-10-69

Published: 27 October 2009

Additional files

Additional file 1:

FST analyses of the five different sets of ASMs among the 74 YCC samples. This file lists the results of a retrospective FST analysis of all 74 YCC samples grouped into the four genetically defined subgroups or six geographically defined subgroups with each of the five different sets of 47 ASMs.

Format: XLS Size: 23KB Download file

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Additional file 2:

rs-numbers of ascertained ASMs and additional information. This file lists the rs-numbers and additional information of two sets of ASMs identified in our study. The 47 ASM set represents the final set of 47 ASMs identified by the pairwise FST 4gen procedure. The 34 ASM set represents a further reduction of this 47ASM set.

Format: XLS Size: 26KB Download file

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Additional file 3:

TaqMan assay. Primer sequences and additional information for the SNPs genotyping using the TaqMan assay.

Format: XLS Size: 23KB Download file

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