Table 4

Survey of services available for LGMD gene mutations

Laboratory

Gene Panel

Genes Tested

Pricing

TAT


Athena Dx Worcester, MA

Yes

(9 genes)

CAPN3, SG's, DYSF, CAV3, FKRP, LMNA

$10,790.00

(total)

5-6 weeks


Nationwide Children's Ohio State

No

CAPN3, SG's, DYSF, CAV3, FKRP, LMNA

$874.50-$1790.75 (per gene)

(varies by size)

4 weeks


Prevention Genetics Marshfield, WI

No

CAPN3, DYSF, FKRP, LAMA2, SGCA, SGCB

(6 genes singly sequenced)

$390.00-$2990.00

(per gene)

(varies by size)

40 days/gene


U. of Utah

Yes (2 genes)

DYSF & CAPN3

$1500.00

(total)

8 weeks


U of Iowa

Yes (3 genes)

(panel)*

SGCA, SGCB, FKRP

CAPN3, LMNA, FKRP, POMT1, POMT2, POMGnT, FCMD**

$905panel*

$462-1781

(per gene)

(varies by size)

2-4 wks


Data gathered from GeneTests http://www.genetests.org webcite and telephone survey of available services for LGMD gene testing. * The U of Iowa panel tests for three known mutations only, if none is positive then the entire FKRP gene is sequenced. **7 genes singly sequenced. (Note that the survey was done in April, 2009 and the services fortunately are constantly being expanded and improved.)

Bennett et al. BMC Genetics 2009 10:66   doi:10.1186/1471-2156-10-66

Open Data