Schematic of an eQTL hotspot, a locus identified to affect transcript abundances for many genes. Directly affected are genes in cis, some of which, the 'cis regulators', propagate the 'perturbation' to other genes. Among cis regulated genes are the putative cis regulators identified by BN.full (yellow) as well as targeted in vivo experimentation (red).
Millstein et al. BMC Genetics 2009 10:23 doi:10.1186/1471-2156-10-23