Additional File 3.

Phylogenetic neighbor-joining tree showing the phylogenetic relationships among histone H2A.Z-1 and H2A.Z-2 protein forms. The reconstruction was carried out by calculating theee evolutionary amino acid p-distances from the H2A sequences of all the organisms analyzed (see Additional file 2). Histone H2A.Z-1 variants are indicated in pink, H2A.Z-2 variants are indicated in purple and H2A.Z-e sequences from early chordates are indicated in brown. Histone variants from protostomes, plants and fungi/protists are indicated in blue, while the root of the tree is labeled in black. Variant sequences predicted from databases and complete/draft genomes data are indicated by PRED near the species name. Numbers for interior nodes indicate BP/CP confidence values. Numbers in colored boxes and in boldface account for the bootstrap values obtained in the reconstruction of the maximum parsimony trees using all the informative positions in the alignment. Confidence values were based on 1000 replications and are only shown if at least one of the values is >50%.

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Eirín-López et al. BMC Evolutionary Biology 2009 9:31   doi:10.1186/1471-2148-9-31