Table 1

Characterisation of lophotrochozoan/non-bilaterian specific genes.

EST

Information from BLAST match

Domains

Cnidaria

Placozoa

Porifera


pl_xlvo_20b10

Nucleoporin 205 kDa

None predicted

+

-

-


pl_xlvo_22d01

Only matches predicted proteins

None predicted

+

-

-


pl_xlvo_24g08

(Contig86)

Calcium dependent mitochondrial carrier protein

EF-hand calcium binding domain (two domains), flagellar calcium binding domain, possibly involved in motility

+

-

-


pl_xlvo_26e03

MAR-binding filament-like protein 1 from plants, similar to IQ motif containing E from zebrafish

IQ motif - binding site for EF-hand proteins

-

+

-


pl_xlvo_39g10

Lactoylglutathione lyase from plants, glutathione S-transferase from anemone

Soluble glutathione S-transferase C-terminal domain - detoxification of reactive electrophilic compounds and in metabolite biosynthesis

+

-

-


pl_xlvo_43h12

(Contig163)

Membrane-associated protein from cyanobacteria

Methyltransferase type 11 - modifies DNA, RNA, proteins and small molecules for regulatory purposes

-

+

-


pl_xlvo_44b10

Endonuclease I

Endonuclease I, Bacterial, periplasmic. Generates double stranded breaks in DNA.

+

-

-


pl_xlvo_46h11

(Contig270)

Regulatory P-domain containing protein

Uncharacterised conserved protein

-

-

+


pl_xlvo_47g05

Putative alpha-amylase from slime mould

Glycosyl hydrolase, family 13, catalytic region - hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety

+

+

+


pl_xlvo_53g01

Apextrin from coral

Kringle domain - thought to play a role in binding mediators, such as membranes, other proteins or phospholipids, and in the regulation of proteolytic activity

Membrane attack complex components/perforin signature - forms transmembrane channels which disrupt the phospholipid bilayer of target cells, leading to cell lysis and death

+

-

-


pl_xlvo_56c06

(Contig381)

Regulatory P-domain containing protein

WD40 repeat - signal transduction, transcriptional control, cell-cycle control and regulation of apoptosis

-

-

+


Domain prediction and descriptions are from INTERPROSCAN and/or PROSITE. Three columns at right side show presence/absence (+/-) of orthologue for each EST in non-bilaterian genomes searched. The entire sequences of these ESTs are available under GenBank accession numbers GQ381295 to GQ381305.

Takahashi et al. BMC Evolutionary Biology 2009 9:240   doi:10.1186/1471-2148-9-240

Open Data