Figure 2.

Analysis of fixed versus polymorphic retrotransposon insertions. (A) Analysis of average GC content flanking polymorphic (P, white) and fixed (F, gray) retrotransposons. GC content was calculated in 5 kb flanking the repeat. The number of repeat instances is also indicated. GC content is significantly higher for regions flanking fixed compared to polymorphic Alus ; the same holds for SVAs. (B) Analysis of polymorphic (white) and fixed (gray) retrotransposon relative frequency in different isochores (L1 to H3, ordered from 1 to 5, as described in [20]). Fixed Alus are significantly enriched in heavy isochores compared to polymorphic instances.

Pozzoli et al. BMC Evolutionary Biology 2008 8:99   doi:10.1186/1471-2148-8-99
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