BMC Evolutionary Biology

official impact factor 3.70

Open Access Research article

Identification of the Otopetrin Domain, a conserved domain in vertebrate otopetrins and invertebrate otopetrin-like family members

Inna Hughes1, Jonathan Binkley2, Belen Hurle3, Eric D Green3,4, NISC Comparative Sequencing Program3,4, Arend Sidow2 and David M Ornitz1*

Author Affiliations

1 Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA

2 Departments of Genetics and Pathology, Stanford University Medical Center, Stanford, CA 94305, USA

3 Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA

4 NIH Intramural Sequencing Center (NISC), National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA

For all author emails, please log on.

BMC Evolutionary Biology 2008, 8:41 doi:10.1186/1471-2148-8-41

Published: 6 February 2008

Additional files

Additional File 1:

CLUSTALW alignment of known and predicted ODP family members. The sources of the protein sequences utilized in this alignment are listed in Table 1. Predicted TM domains are shaded (tan) and numbered TM1 to TM12. Inter-TM loops are numbered L1 to L11. Otopetrin Domains OD-I, -II, and -III are shaded in green, purple, and blue, respectively. Dashes indicate sequence gaps.

Format: PDF Size: 2.3MB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data