Table 4

Different fates of WGD paralogs involved in RSC complex.

WGD gene pair

Duplication type

Essential

Comments

RSC1/RSC2

intra-complex

n/n, synthetic lethal

mutually exclusive, both indispensable during fermentation, different deletion phenotypes

RSC3/RSC30

intra-complex

y/n

heterodimers, equal proportions, RSC30 duplicated post-WGD

RSC6/SNF12

bi-complex

n/n, phenotypic supression*

subfunctionalization

*) Phenotypic suppression of RSC6 and SNF11, an another SWI/SNF component, is revealed by the E-MAP assay [47].

Szklarczyk et al. BMC Evolutionary Biology 2008 8:337   doi:10.1186/1471-2148-8-337