Table 1

Different measures used for asserting domain combination tendencies

Measure

Abbr.

Description

Reference


Co-occurrence

NCO

Number of domains that are found at least once in the same proteins as the given domain

[7]

Number of neighbours

NN

Number of direct neighbours found for a given domain

[26]

Number of triplets

NTRP

For a given domain A, number of different combinations X – A – Y, where X and Y are domains or N- or C-termini

[12]

Weighted bigram frequency index

πi

See original paper for exact definition

[32]

Domain versatility index

DV I

Strength of the relationship between the number of occurrences and the number of neighbours

this study


Weiner et al. BMC Evolutionary Biology 2008 8:285   doi:10.1186/1471-2148-8-285

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