(A) Location of the dentin sialophosphoprotein (DSPP) and other SIBLING genes on human chromosome 4.(B) Homologous region on chicken chromosome 4 and putative location of DSPP. Note that the SIBLING cluster is more compact in chicken than in human. OC116 and MEPE are orthologs. (C) Result of the similarity search in the candidate region between DMP1 and SPARCL1 using human DSPP exon 2. Chicken Ψ-DSPP exon 2 was found 5,800 bp from DMP1. (D) Alignment of chicken and crocodile DSPP exon 2 showing 54% nucleotide identity. See the NCBI website for gene descriptions corresponding to the symbols.
Sire et al. BMC Evolutionary Biology 2008 8:246 doi:10.1186/1471-2148-8-246