Table 2

Go categories and relative divergence rates (dN/dS) in hominid and murid lineages

Go categories within "biological process"
dN/dS (ω)
hominid
dN/dS (ω)
murid
p-value

GO: Organelle organization and biogenesis
0.093797
0.136622
0.34
GO: Carbohydrate metabolism
0.094282
0.061524
0.17
GO: Energy pathways
0.095999
0.06409
0.25
GO: Protein transport
0.1000621
0.056915
0.10
GO: Cell organization and biogenesis
0.102521
0.11164
0.75
GO: Cytoskeleton organization and biogenesis
0.106537
0.123027
0.68
GO: Protein biosynthesis
0.10841
0.076408
0.092
GO: Transcription
0.1093033
0.085371
0.49
GO: Cell growth and/or maintenance
0.112558
0.078195
0.02
GO: Cytoplasm organization and biogenesis
0.115938
0.124335
0.80
GO: Catabolism
0.117659
0.107771
0.70
GO: Transport
0.118198
0.076005
0.059
GO: Amino acid and derivative metabolism
0.118466
0.105378
0.64
GO: Protein metabolism
0.118917
0.09077
0.06
GO: Biosynthesis
0.120925
0.09066
0.054
GO: Physiological process
0.12305
0.08881
0.0001
GO: Cell proliferation
0.125543
0.055601
0.03
GO: Metabolism
0.12623
0.0897
0.0001
GO: Nucleobase et al*.
0.128449
0.07981
0.01
GO: Cell cycle
0.137136
0.055177
0.01
GO: Response to stress
0.140927
0.064359
0.03
GO: DNA metabolism
0.154415
0.062976
0.0028
GO: Protein modification
0.170329
0.116675
0.21
GO: Lipid metabolism
0.171853
0.124668
0.17
GO: Biological_process unknown
0.2353
0.17011
0.001
GO: Cell communication
0.2439164
0.159463
0.17

*Nucleobase, nucleoside, nucleotide and nucleic acid metabolism.

Only those categories of biological processes with at least 5 genes in both lineages are listed. The p-value of the test comparing the average dN/dS (ω) ratio between hominid and murid lineages is given for each category (p-value). None of the category showed an accelerated evolution in hominid or rodent, given the average genome difference between lineages.

Prugnolle et al. BMC Evolutionary Biology 2008 8:223   doi:10.1186/1471-2148-8-223