Figure 1.

Arrestin family tree. Annotated arrestin proteins from select sequenced genomes were used to construct a neighbor-joining phylogenetic tree. The visual/beta arrestin proteins branch from the remainder of the tree with a bootstrap confidence score of 100 (arrow). The scale bar shows the number of substitutions per site. Taxonomy abbreviations follow: str_protist, stramenopiles 9STRA (Protista, Stramenopiles); par_protist, Paramecium tetraurelia (Protista, Alveolata); sl_mold, slime mold Dictyostelium discoideum (Protista, Mycetozoa); fis_yeast, fission yeast Schizosaccharomyces pombe; asc_fungus, Emericella nidulans (Fungi/Ascomycota); hydra, Hydra magnipapillata (Cnidaria); worm, nematode C. elegans (Nematoda); fly, Drosophila m. (Arthropoda); protochord, Ciona intestinalis (Urochordata); fish, Danio rerio (zebrafish; Vertebrata). Vertebrate visual/beta arrestins are given in HUGO nomenclature [see Additional file 1]: S-antigen, SAG (aka, rod arrestin, arrestin 1); arrestin 3, ARR3 (aka, cone arrestin, X-arrestin, arrestin 4); arrestin, beta 1, ARRB1 (aka, arrestin 2); and arrestin, beta 2, ARRB2 (aka, arrestin 3).

Alvarez BMC Evolutionary Biology 2008 8:222   doi:10.1186/1471-2148-8-222
Download authors' original image