The dependence of the Pearson correlation coefficient of entropy profiles cc(N, X) between two subgroups N and X of the same ortholog group and three different measurements of properties of ortholog group. The green oval in each figure indicates the information used in the corresponding measurement a) global property: the ratio of distance between the last common ancestors of the genes in subgroups X and N and the average distance between sequences from the different subgroups. b) local property: the average entropy of the alignment of sequences in N c) the semi-local property: the correlation of cc(N, Y) with value of cc(N, Y) computed based on entropy profile of N to subgroup Y different than X.
Przytycka et al. BMC Evolutionary Biology 2008 8:208 doi:10.1186/1471-2148-8-208