Table 2 |
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|
Corrected ratio of nonsynonymous to synonymous substitution in several FMDV populations |
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|
Viral populationa |
dn/ds (Molecular clones)b |
dn/ds (Consensus sequences)c |
|
|
||
|
RAp35 |
0.16 |
N.D |
|
RAp45 |
0.08 |
0.09 (MALRS) |
|
RAp60 |
0.07 |
0.08 (MARLS) |
|
RA0p35 |
0.12 |
N.D. |
|
C-S8p260p3d |
N.D. |
0.63 (C-S8c1) |
|
MARLS |
1.21d |
0.65 (C-S8c1) |
|
|
||
|
N.D. not determined. aThe viral populations analyzed are those described in Figure 1 and Methods. bdn/ds is the ratio of nonsynonymous mutations (corrected per nonsynonymous site) to synonymous mutation (corrected per synonymous site), calculated as described in Methods [85,86]. Values correspond to calculations using nucleotide sequences from molecular clones (as described in Table 1). cdn/ds calculated as in b, applied to consensus nucleotide sequences, compared with the corresponding parental clone (given in parenthesis). dThis value was calculated with biological clones derived from MARLS, using the L (leader) protease-and capsid-coding regions. |
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Ojosnegros et al. BMC Evolutionary Biology 2008 8:207 doi:10.1186/1471-2148-8-207 |
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