Table 5

Over-representation of gene classes in clusters.

Among Species

D. simulans

Both

Male specific sperm protein

Protein of unknown function UPF0131

Glycoside hydrolase, family 22, lysozyme

Fruit fly testis-specific protein

Chorion 2

Lysozyme c

Developmental protein

Insect vitellogenin

LYZ1

Establishment of localization

Uncharacterized conserved protein

Antimicrobial

Exocrine system development

Antibacterial humoral response

Bacteriolytic enzyme

Glycerol kinase activity

Antimicrobial humoral response

Chorion

Localization

Cell wall catabolism

External encapsulating structure

Multigene family

Defense response to bacteria

Lysozyme activity

Reproduction

Eggshell formation

Polysaccharide degradation

Salivary gland determination

Female gamete generation

Sexual reproduction

Salivary gland development

Gametogenesis

Structural constituent of chorion (sensu Insecta)

Spermatogenesis

Glycosidase

Tandem repeat

Humoral defense mechanism (sensu Protostomia)

Transport

Humoral immune response

Transporter activity

Hydrolase activity, acting on glycosyl bonds

Insect chorion formation

Membrane lipid metabolism

Phospholipid metabolism

Response to bacteria

Response to pest, pathogen or parasite

Signal

Structural molecule activity

Sulfation

Vitellogenesis

Classes presented are those with a p-value < 0.05 as determined by DAVID (see Methods) for the clusters identified with a window size of 2 and a p-value cutoff of p < 0.001.

Mezey et al. BMC Evolutionary Biology 2008 8:2   doi:10.1186/1471-2148-8-2