Transposases vs. IRs and DRs. Comparative overview of IS sequence features. A. Dendrogram representing an alignment of 227 transposases. The first common node of each family was pointed out on the left tree side. Subgroups of family IS4 are mentioned on the right tree side. Individual IS names were removed for clarity. B. Consensus sequences (5' to 3') of left (upper line) and right (lower line) DNA extremities of distinct subgroups/families. '+' symbols are used when the highest conservation level is shared by more than one residue. Percentages of nucleotide conservation at all positions are indicated by black bars. Decimal nucleotide numbering is marked by dotted vertical lines. Full alignments that generated each consensus can be found in Additional files 1 to 10. Note that in the case of family IS701, the exposed consensus does not represent the entire family. For further details, see Additional file 8. IRL, left TIR; IRR, right TIR. C. Target duplication length range in bps.
De Palmenaer et al. BMC Evolutionary Biology 2008 8:18 doi:10.1186/1471-2148-8-18