Research article
The repertoire of G protein-coupled receptors in the sea squirt Ciona intestinalis
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* Corresponding author: Narayanan Manoj nmanoj@iitm.ac.in
Department of Biotechnology, Bhupat and Jyothi Mehta School of Biosciences Building, Indian Institute of Technology Madras, Chennai 600036, India
BMC Evolutionary Biology 2008, 8:129 doi:10.1186/1471-2148-8-129
Published: 1 May 2008Additional files
Additional file 1:
Protein sequences of all Ciona GPCRs identified in this study in FASTA format
Format: PDF Size: 141KB Download file
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Additional file 2:
Ciona GPCRs with homologs in Humans and other genomes (Sheet 1) and EST-HITS of Ciona GPCRs sorted by developmental stage/tissue (Sheet 2)
Format: XLS Size: 626KB Download file
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Additional file 3:
Domain architecture of LDLRR-GPCR/LGR-like/GLHR receptor cluster in Ciona
Format: PDF Size: 272KB Download file
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Additional file 4:
Multiple sequence alignment of human and rat PTHRs with homologs from Ciona. Alignment was generated in MAFFT using gap penalty of 1.53 and offset value 0.123. Scoring matrix is based on JTT200. Colored amino acids are used to refer functionally important residues known in human and rat PTHR1 and their putative homologs in Ciona and human PTHR2. Furthermore transmembrane regions are colored and sequence conservation and similarity represented symbolically.
Format: PDF Size: 103KB Download file
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Additional file 5:
The GRAFSCM (Glutamate, Rhodopsin, Adhesion, Frizzled, Secretin, cAMP GPCR-like, Methuselah-like) phylogenetic tree in standard Newick format.
Format: TRE Size: 4KB Download file
Additional file 6:
The non-(LDLRR-GPCR/LGR) Rhodopsin phylogenetic tree in standard Newick format
Format: TRE Size: 4KB Download file