Table 1 |
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|
GO categories listed for domain families with statistically significant bias (p-value < 0.01) with respect to increasing, decreasing and stable individual spacers. |
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|
Decreasing |
Stable |
Increasing |
GO annotation |
P-value |
|
|
||||
|
6 (9.8) |
47 (64.9) |
38 (16.3) |
transferase activity, transferring glycosyl groups |
0.0000 |
|
12 (11.2) |
52 (74.2) |
40 (18.7) |
replicative cell aging |
0.0000 |
|
25 (11.7) |
58 (77.7) |
26 (19.6) |
endoplasmic reticulum membrane |
0.0000 |
|
24 (20.6) |
112 (136.9) |
56 (34.5) |
positive regulation of cell proliferation |
0.0001 |
|
0 (11.7) |
93 (77.7) |
16 (19.6) |
ubiquitin cycle |
0.0005 |
|
14 (32.1) |
231 (213.2) |
54 (53.7) |
membrane fraction |
0.0029 |
|
5 (8.6) |
70 (57.1) |
5 (14.4) |
chemotaxis |
0.0052 |
|
0 (8.9) |
66 (59.2) |
17 (14.9) |
ubiquitin-dependent protein catabolism |
0.0068 |
|
4 (13.5) |
91 (89.9) |
31 (22.6) |
mitosis |
0.0074 |
|
30 (33.5) |
205 (222.5) |
77 (56) |
transcription |
0.0082 |
|
2 (8.2) |
66 (54.2) |
8 (13.6) |
protein folding |
0.0084 |
|
4 (14.9) |
111 (99.1) |
24 (25) |
G-protein coupled receptor protein signaling pathway |
0.0089 |
|
|
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|
First three columns show the observed and expected number (in parentheses) of decreasing, stable and increasing spacers for different GO categories. Categories, contributing more than 2/3 of the χ2 value due to excess (in bold) or shortage (in italic) of observed families are highlighted. The last column lists p-value of Pearson χ2-test. |
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|
Wolf et al. BMC Evolutionary Biology 2007 7:19 doi:10.1186/1471-2148-7-19 |
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