BMC Evolutionary Biology

official impact factor 3.70

Open Access Research article

The distribution and evolutionary history of the PRP8 intein

Margaret I Butler*, Jeremy Gray, Timothy JD Goodwin and Russell TM Poulter

Author Affiliations

Department of Biochemistry, University of Otago, P.O. Box 56, Dunedin, New Zealand

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BMC Evolutionary Biology 2006, 6:42 doi:10.1186/1471-2148-6-42

Published: 31 May 2006

Additional files

Additional File 1:

SNAP XY plots of the homing endonuclease encoding regions of the PRP8 and VMA inteins. These represent the cumulative behaviour of the average synonymous and non-synonymous substitutions across the coding region. The analysis was done at the SNAP site [40]. The positions of codons are indicated below the x-axis. The y-axis indicates the cumulative number of nucleotide changes causing synonymous (red) or non-synonymous (green) amino acid changes.

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