Research article
Evolution and origin of merlin, the product of the Neurofibromatosis type 2 (NF2) tumor-suppressor gene
-
* Corresponding author: Long-Sheng Chang lchang@chi.osu.edu
1 Institute of Cytology and Genetics, Russian Academy of Sciences, 10 Lavrent'ev Ave., 630090, Novosibirsk, Russia
2 Center for Childhood Cancer, Children's Research Institute, Children's Hospital and Department of Pediatrics, The Ohio State University, 700 Children's Drive, Columbus, OH 43205-2696, USA
BMC Evolutionary Biology 2005, 5:69 doi:10.1186/1471-2148-5-69
Published: 2 December 2005Additional files
Additional File 1:
Complete amino acid sequence alignment of the merlin and ERM proteins. Letters shaded in grey illustrate the conservation pattern of aligned sequences. The names of the merlin proteins from various species are shown in yellow. The conserved residues of the 'Blue Box' are also shaded in yellow. The positions of residues discussed in the text are colored in red. Blue letters denote the conserved residues within the predicted α-helical domain. Numbers indicated at the end of each sequence refer to the positions of the last residue within each protein analyzed.
Format: PDF Size: 3.2MB Download file
This file can be viewed with: Adobe Acrobat Reader
