Research article
Evolution of the relaxin-like peptide family
-
* Corresponding author: Ross AD Bathgate r.bathgate@hfi.unimelb.edu.au
1 Howard Florey Institute of Experimental Physiology and Medicine, University of Melbourne, Australia
2 Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
BMC Evolutionary Biology 2005, 5:14 doi:10.1186/1471-2148-5-14
Published: 12 February 2005Additional files
Additional File 1:
Phylogeny of cluster A- relaxin-3 and INSL5. Phylogeny of Cluster A constructed from a ClustalW alignment of the B and A domain amino acid sequences from relaxin 3 and INSL5 peptides. Consensus tree generated from MP (Protpars in PHYLIP), ML (TreePuzzle) and NJ (Neighbour in PHYLIP) methods and edited in Treeview to minimize species tree incongruence. Human insulin was used as an outgroup. Where possible, confidence values are shown at branches: * >50%, ** >75%, all other branches are inferred. Hsa = Homo sapiens, Pt = Pan troglodytes, Mm = Mus musculus, Rn = Rattus norvegicus, Cf = Canis familiaris, Ss = Sus scrofa, Xt = Xenopus tropicalis, Dr = Danio rerio, Tr = Takifugu rubripes, Gg = Gallus gallus, Om = Oncorhynchus mykiss.
Format: DOC Size: 26KB Download file
This file can be viewed with: Microsoft Word Viewer
Additional File 2:
Phylogeny of cluster B- relaxin-1, 2, INSL3, INSL4 and INSL6. Consensus phylogeny of Cluster B constructed from a ClustalW alignment of the B and A domain amino acid sequences from relaxin 1, 2, INSL3, INSL4, INSL6 peptides. Consensus tree generated from MP (Protpars in PHYLIP), ML (TreePuzzle) and NJ (Neighbour in PHYLIP) methods and edited in Treeview to minimize species tree incongruence. Human insulin was used as an outgroup. Where possible, confidence values are shown at branches: * >50%, ** >75%, all other branches are inferred. Hsa = Homo sapiens, Pt = Pan troglodytes, Mmul = Maca mulatta, Mm = Mus musculus, Rn = Rattus norvegicus, Cf = Canis familiaris, Ss = Sus scrofa, Re = Rana esculenta, Me = Macropus eugenii, Xl = Xenopus laevis, Xt = Xenopus tropicalis, Dr = Danio rerio, Tr = Takifugu rubripes.
Format: DOC Size: 26KB Download file
This file can be viewed with: Microsoft Word Viewer