Research article
Is autoinducer-2 a universal signal for interspecies communication: a comparative genomic and phylogenetic analysis of the synthesis and signal transduction pathways
1 Department of Genome Analysis, GBF – German Research Center for Biotechnology, Braunschweig, Germany
2 Institute for Microbiology and Genetics, University of Göttingen, Göttingen, Germany
3 Research Group Microbial Communication, GBF – German Research Center for Biotechnology, Braunschweig, Germany
BMC Evolutionary Biology 2004, 4:36 doi:10.1186/1471-2148-4-36
Published: 29 September 2004Additional files
Additional File 1:
Supplementary Table s1. Presence of AI-2 synthesis and detection genes in 138 completed genomes of the KEGG database (July 2003). Abbreviations: luxS, AI-2 synthetase/SRH cleavage enzyme; pfs, SAH-nucleosidase enzyme; sahH, SAH hydrolase; metH and metH, methionine synthetase; metK SAM synthetase; luxP, AI-2 binding protein; luxQ, membrane bound hybrid sensor kinase; luxU, histidine phosphorelay protein ; luxO response regulator. See Fig. 1 for further information on the synthesis pathway and Fig. 2 for the phosporelay detection cascade. Organisms shaded violet contain neither luxS nor sahH.
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Additional File 2:
Supplementary Table s2. The accession numbers of the genes in Supplementary Table s1. Abbreviations as in Supplementary Table s1.
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Additional File 3:
Supplementary Table s3. Presence of the Salmonella lsr gene homologs in the completed genomes of the KEGG database (July 2003). Abbreviations as in Supplementary Table s1. X denotes bi-directional hits, ? denotes unidirectional hits.
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