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Correlation between ortholog substitution levels and the substitution levels between the most closely related paralogs for lineage specific expansions (Figure 3) |
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| Lineagea |
Slopeb |
r2c |
Pd |
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| Human specific (1-2a) |
2.0 × 10-1 |
7.8 × 10-2 |
1.6 × 10-34 |
| Mammalian specific (2-2a) |
2.1 × 10-1 |
2.2 × 10-1 |
2.7 × 10-114 |
| Vertebrate and before (3-2a) |
8.2 × 10-2 |
7.3 × 10-2 |
9.9 × 10-132 |
| S. cerevisiae specific (1-2b) |
8.3 × 10-1 |
4.6 × 10-1 |
1.7 × 10-58 |
| S. cerevisiae – C. albicans (2-2b) |
4.6 × 10-1 |
4.2 × 10-1 |
3.4 × 10-18 |
| Yeast and before (3-2b) |
3.3 × 10-1 |
2.1 × 10-1 |
2.8 × 10-54 |
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a Lineage specific expansions for which comparisons were performed (numbers in parentheses correspond to Figure 3a and 3b) b Slope of the linear regression line (i.e. y from the equation y = mx + b) c Square of the correlation coefficient (corresponds to the fraction of variation in ortholog evolutionary rates explained by the variation in paralog evolutionary rate) d P-value for correlation coefficient | |||
Jordan et al. BMC Evolutionary Biology 2004 4:22 doi:10.1186/1471-2148-4-22 |
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