Table 4

Correlation between ortholog substitution levels and the substitution levels between the most closely related paralogs for lineage specific expansions (Figure 3)

Lineagea

Slopeb

r2c

Pd


Human specific (1-2a)

2.0 × 10-1

7.8 × 10-2

1.6 × 10-34

Mammalian specific (2-2a)

2.1 × 10-1

2.2 × 10-1

2.7 × 10-114

Vertebrate and before (3-2a)

8.2 × 10-2

7.3 × 10-2

9.9 × 10-132

S. cerevisiae specific (1-2b)

8.3 × 10-1

4.6 × 10-1

1.7 × 10-58

S. cerevisiae C. albicans (2-2b)

4.6 × 10-1

4.2 × 10-1

3.4 × 10-18

Yeast and before (3-2b)

3.3 × 10-1

2.1 × 10-1

2.8 × 10-54


a Lineage specific expansions for which comparisons were performed (numbers in parentheses correspond to Figure 3a and 3b) b Slope of the linear regression line (i.e. y from the equation y = mx + b) c Square of the correlation coefficient (corresponds to the fraction of variation in ortholog evolutionary rates explained by the variation in paralog evolutionary rate) d P-value for correlation coefficient

Jordan et al. BMC Evolutionary Biology 2004 4:22   doi:10.1186/1471-2148-4-22

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