Table 2 

Correlation between ortholog substitution levels and the number of paralogs 

Species^{a} 
Slope^{b} 
r^{2c} 
P^{d} 


Human – Mouse 
1.0 × 10^{4} 
3.0 × 10^{3} 
7.2 × 10^{13} 
Drosophila – Anopheles 
8.0 × 10^{4} 
5.2 × 10^{3} 
9.6 × 10^{10} 
S. cerevisiae – C. albicans 
4.7 × 10^{3} 
9.8 × 10^{3} 
6.0 × 10^{9} 
E. coli – Y. pestis 
6.0 × 10^{4} 
3.0 × 10^{4} 
4.2 × 10^{1} 
B. subtilis – B. halodurans 
7.0 × 10^{4} 
2.0 × 10^{4} 
4.9 × 10^{1} 
P. horikoshii – P. furiosis 
2.5 × 10^{3} 
1.5 × 10^{3} 
1.4 × 10^{1} 


^{a }Species for which comparisons were performed ^{b }Slope of the linear regression line (i.e. y from the equation y = mx + b) ^{c }Square of the correlation coefficient (corresponds to the fraction of variation in ortholog evolutionary rates explained by the variation in the number of paralogs) ^{d }Pvalue for correlation coefficient 

Jordan et al. BMC Evolutionary Biology 2004 4:22 doi:10.1186/14712148422 