|
Statistical significance of the differences in evolutionary rates between groups of proteins with different numbers of interactions. |
|
| Bin (# interactions) comparisonsa |
Pb |
|
|
|
| S. cerevisiae – S. pombe |
|
| 41 – 60 vs. 1 – 40 |
8.3 × 10-4 |
| 31 – 60 vs. 1 – 30 |
2.4 × 10-2 |
| 21 – 60 vs. 1 – 20 |
1.7 × 10-4 |
| H. pylori 26695 – H. pylori J99 |
|
| 21 – 55 vs. 1 – 20 |
1.5 × 10-1 |
| 15 – 55 vs. 1 – 14 |
1.8 × 10-1 |
| 11 – 55 vs. 1 – 10 |
3.2 × 10-1 |
| H. pylori 26695 – C. jejuni |
|
| 21 – 47 vs. 1 – 20 |
9.8 × 10-1 |
| 11 – 47 vs. 1 – 10 |
5.1 × 10-1 |
|
a Orthologous pairs of proteins were placed into bins based on the number of protein-protein interactions (Figure 3). b P-value for the Student's ttest comparing the mean evolutionary rates between orthologs for bins with distinct ranges in the number of protein-protein interactions. | |
Jordan et al. BMC Evolutionary Biology 2003 3:1 doi:10.1186/1471-2148-3-1 |
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