## Table 1 |
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Possible terms included in regression analyses |
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Factor |
States |
Effect type |
Effect measured |
Relevant models |

Genotype | 10 | Fixed or random | F1 cross genotype of flies | A,B,C,D,E,F |

Diet | 2 | Fixed | Diet that flies were reared and phenotyped on | A,B,C,D,E,F |

Load | Continuous | Daily bacterial load, natural log transformed | A,B,C,D | |

Day | 5 | Fixed | Day post-infection | A,B,C,D,E,F |

Uninfected fecundity | Continuous | Daily fecundity of uninfected flies | A,B | |

Genotype*Diet | 20 | Fixed | Differential effect of diet on each genotype | A,C,E |

Genotype*Load | Continuous | Differential effect of pathogen load on each genotype | A,C | |

Diet*Load | Continuous | Differential effect of pathogen load on each diet | A,B,C,D | |

Diet*Day | 10 | Fixed | Differential dynamics on each diet | B,D |

Load*Day | Continuous | Differential dynamics of tolerance | B,D | |

Genotype*Diet*Load | Continuous | Differential effect of diet on tolerance | A,C | |

Diet*Load*Day | Continuous | Differential effect of diet on tolerance dynamics | B,D |

*represents an interaction between factors.

See Methods for full models.

Howick and Lazzaro

Howick and Lazzaro *BMC Evolutionary Biology* 2014 **14**:56 doi:10.1186/1471-2148-14-56